BRD1 Protein (AA 556-688) (His tag,DYKDDDDK Tag)

N° du produit ABIN2669686

Détail du produit

Antigène: BRD1 (Bromodomain Containing 1 (BRD1))

Type de proteíne: Recombinant

Attributs du protein: AA 556-688

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette BRD1 protéine est marqué à la His tag,DYKDDDDK Tag.

Application: Binding Studies (Bind), Screening Assay (ScA)

Attributs du produit: The peptide corresponding to amino acids 556-688 that contains the bromodomain sequences of BRD1 (accession number NP_055392.1) was expressed in E. coli and contains an N-terminal His tag and C-terminal FLAG tag with an observed molecular weight of 21.5 kDa.

Information d'application

Indications d'application: Recombinant BRD1 (556-688) is suitable for use in binding assays, inhibitor screening, and selectivity profiling.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -80 °C

Stockage commentaire: Recombinant proteins in solution are temperature sensitive and must be stored at -80°C to prevent degradation.

Détail du antigène

Antigène: BRD1 (Bromodomain Containing 1 (BRD1))

Autre désignation: BRD1 (BRD1 Produits)

Sujet: Bromodomain-containing protein 1 (BRD1) belongs to the BET subclass of proteins, which are characterized by two N-terminal bromodomains and one ET (Extra Terminal) domain. BRDs associate with chromatin through their bromodomains that recognize acetylated histone lysine residues. Bromodomains function as 'readers' of these epigenetic histone marks and regulate chromatin structure and gene expression by linking associated proteins to the acetylated nucleosomal targets. The ET domain functions as a protein binding motif and exerts atypical serine-kinase activity. The BET family consists of several members that function in the regulation of transcriptional activation and chromatin remodeling.

Poids moléculaire: 21.5 kDa