TBK1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2712379

Détail du produit

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette TBK1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human TBK1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: TBK1 (TANK-Binding Kinase 1 (TBK1))

Autre désignation: Tbk1 (TBK1 Produits)

Synonymes: nak Protein, t2k Protein, TBK1 Protein, wu:fk70c05 Protein, zgc:136548 Protein, NAK Protein, T2K Protein, 1200008B05Rik Protein, AI462036 Protein, AW048562 Protein, TANK binding kinase 1 L homeolog Protein, TANK binding kinase 1 Protein, TANK-binding kinase 1 Protein, tbk1.L Protein, TBK1 Protein, tbk1 Protein, Tbk1 Protein

Sujet: The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

Poids moléculaire: 83.5 kDa

NCBI Accession: NP_037386

Pathways: Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome