CRLF2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2712563

Détail du produit

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CRLF2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CRLF2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

Autre désignation: Crlf2 (CRLF2 Produits)

Synonymes: CRLF2 Protein, CRL2 Protein, CRLF2Y Protein, TSLPR Protein, CRLM2 Protein, Ly114 Protein, Tpte2 Protein, Tslpr Protein, Crl2 Protein, cytokine receptor like factor 2 Protein, cytokine receptor-like factor 2 Protein, CRLF2 Protein, Crlf2 Protein

Sujet: This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 41.8 kDa

NCBI Accession: NP_071431