CYR61 Protéine
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- Antigène Voir toutes CYR61 Protéines
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
- Attributs du produit
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- Recombinant human CYR61 protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by the dose-dependent stimulation of the proliferation of murine 3T3 cells. The expected ED50 for this effect is 2.0-3.0ug/mL.
- Top Product
- Discover our top product CYR61 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- CYR61 (Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
- Autre désignation
- Cyr61 (CYR61 Produits)
- Synonymes
- CCN1 Protein, GIG1 Protein, IGFBP10 Protein, ccn1 Protein, gig1 Protein, Xcyr61 Protein, igfbp10 Protein, MGC69281 Protein, MGC69539 Protein, cyr61-l2 Protein, zgc:158158 Protein, CYR61 Protein, AI325051 Protein, Igfbp10 Protein, cysteine rich angiogenic inducer 61 Protein, cysteine-rich, angiogenic inducer, 61 Protein, cysteine-rich, angiogenic inducer, 61 like 2 Protein, cysteine rich protein 61 Protein, cysteine rich angiogenic inducer 61 S homeolog Protein, CYR61 Protein, Cyr61 Protein, cyr61 Protein, cyr61l2 Protein, cyr61.S Protein
- Sujet
- The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.
- Poids moléculaire
- 39.5 kDa
- NCBI Accession
- NP_001545
- Pathways
- Positive Regulation of Endopeptidase Activity, Growth Factor Binding
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