CLEC4E Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2712869

Détail du produit

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CLEC4E protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CLEC4E protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Wevers, Kaptein, Zijlstra-Willems, Theelen, Boekhout, Geijtenbeek, Gringhuis: "Fungal engagement of the C-type lectin mincle suppresses dectin-1-induced antifungal immunity." dans: Cell host & microbe, Vol. 15, Issue 4, pp. 494-505, (2014) (PubMed).

Détail du antigène

Antigène: CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))

Autre désignation: Clec4e (CLEC4E Produits)

Synonymes: CLECSF9 Protein, MINCLE Protein, C86253 Protein, Clecsf9 Protein, Mincle Protein, CLEC4E Protein, C-type lectin domain family 4 member E Protein, C-type lectin domain family 4, member e Protein, C-type lectin domain family 4, member E Protein, CLEC4E Protein, Clec4e Protein, LOC611538 Protein

Sujet: This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type II transmembrane protein is a downstream target of CCAAT/enhancer binding protein (C/EBP), beta (CEBPB) and may play a role in inflammation. Alternative splice variants have been described but their full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Poids moléculaire: 24.9 kDa

NCBI Accession: NP_055173