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Cofilin 2 Protein (CFL2) (Transcript Variant 2) (Myc-DYKDDDDK Tag)

CFL2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2712946
  • Antigène Voir toutes Cofilin 2 (CFL2) Protéines
    Cofilin 2 (CFL2)
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    • 6
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Cofilin 2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Cofilin-2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product CFL2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    Cofilin 2 (CFL2)
    Autre désignation
    Cofilin-2 (CFL2 Produits)
    Synonymes
    NEM7 Protein, CFL2 Protein, zgc:77288 Protein, cf12 Protein, cofilin 2 Protein, cofilin 2 (non-muscle) Protein, cofilin 2 (muscle) Protein, cofilin 2, muscle Protein, cofilin-2 Protein, CFL2 Protein, cfl2 Protein, Cfl2 Protein, cf12 Protein, LOC100359205 Protein
    Sujet
    This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.
    Poids moléculaire
    18.6 kDa
    NCBI Accession
    NP_619579
    Pathways
    Caspase Cascade in Apoptosis
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