CACNB4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713010

Détail du produit

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CACNB4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CACNB4 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CACNB4 (Calcium Channel, Voltage-Dependent, beta 4 Subunit (CACNB4))

Autre désignation: Cacnb4 (CACNB4 Produits)

Synonymes: CAB4 Protein, CACNLB4 Protein, EA5 Protein, EIG9 Protein, EJM Protein, EJM4 Protein, EJM6 Protein, 3110038O15Rik Protein, Cchb4 Protein, lethargic Protein, lh Protein, CACNB4 Protein, cacnb4.2 Protein, calcium voltage-gated channel auxiliary subunit beta 4 Protein, calcium channel, voltage-dependent, beta 4 subunit Protein, calcium channel, voltage-dependent, beta 4a subunit Protein, CACNB4 Protein, Cacnb4 Protein, cacnb4.1 Protein, cacnb4 Protein, cacnb4a Protein

Sujet: This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5.

Poids moléculaire: 58 kDa

NCBI Accession: NP_000717

Pathways: cAMP Metabolic Process, Skeletal Muscle Fiber Development