CBFA2T3 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713252

Détail du produit

Antigène: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CBFA2T3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CBFA2T3 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CBFA2T3 (Core-binding Factor, Runt Domain, alpha Subunit 2, Translocated To, 3 (CBFA2T3))

Autre désignation: Cbfa2t3 (CBFA2T3 Produits)

Synonymes: A630044F12Rik Protein, AI465270 Protein, AW229127 Protein, Cbfa2t3h Protein, ETO-2 Protein, Eto2 Protein, MTGR2 Protein, MTG16a Protein, MTG16b Protein, ETO2 Protein, MTG16 Protein, ZMYND4 Protein, core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human) Protein, CBFA2/RUNX1 translocation partner 3 Protein, Cbfa2t3 Protein, CBFA2T3 Protein

Sujet: This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(1621)(q24q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5&apos-region of the runt-related transcription factor 1 gene fused to the 3&apos-region of this gene. This gene is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Poids moléculaire: 71 kDa

NCBI Accession: NP_005178