CCNDBP1 Protein (His tag)

N° du produit ABIN2713325

Détail du produit

Antigène: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CCNDBP1 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CCNDBP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 100 mM Arg. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Autre désignation: Ccndbp1 (CCNDBP1 Produits)

Synonymes: CCNDBP1 Protein, dip1 Protein, gcip Protein, DIP1 Protein, GCIP Protein, HHM Protein, AU022347 Protein, Maid Protein, SECC-8 Protein, SSEC-8 Protein, cyclin D1 binding protein 1 Protein, cyclin D-type binding-protein 1 Protein, CCNDBP1 Protein, ccndbp1 Protein, Ccndbp1 Protein

Sujet: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

Poids moléculaire: 40.3 kDa

NCBI Accession: NP_036274