ITGA6 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713733

Détail du produit

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ITGA6 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CD49f / ITGA6 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ITGA6 (Integrin, alpha 6 (ITGA6))

Autre désignation: Cd49f,itga6 (ITGA6 Produits)

Synonymes: CD49f Protein, ITGA6B Protein, VLA-6 Protein, 5033401O05Rik Protein, AI115430 Protein, Cd49f Protein, ITGA6 Protein, inta6 Protein, im:6897425 Protein, itga6 Protein, si:dkey-32o22.1 Protein, wu:fb80g02 Protein, LOC100221694 Protein, si:dkey-18j14.1 Protein, wu:fl20e08 Protein, zgc:113088 Protein, integrin subunit alpha 6 Protein, integrin alpha 6 Protein, integrin subunit alpha 6 L homeolog Protein, integrin, alpha 6a Protein, integrin, alpha 6b Protein, ITGA6 Protein, Itga6 Protein, itga6.L Protein, itga6a Protein, itga6b Protein

Sujet: The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 117.2 kDa

NCBI Accession: NP_000201

Pathways: CXCR4-mediated Signaling Events, Brown Fat Cell Differentiation, Integrin Complex