CDKN2D Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2713883

Détail du produit

Antigène: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CDKN2D protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CDKN2D / p19INK4d (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CDKN2D (Cyclin-Dependent Kinase Inhibitor 2D (p19, Inhibits CDK4) (CDKN2D))

Autre désignation: Cdkn2d,p19ink4d (CDKN2D Produits)

Synonymes: ink4d Protein, p19 Protein, p19-ink4d Protein, CDKN2D Protein, ank2 Protein, INK4D Protein, p19-INK4D Protein, INK4d Protein, p19INK4d Protein, cyclin-dependent kinase inhibitor 2D S homeolog Protein, cyclin dependent kinase inhibitor 2D Protein, cyclin-dependent kinase inhibitor 2D Protein, Cyclin-dependent kinase 4 inhibitor D Protein, cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) Protein, similar to cyclin-dependent kinase inhibitor 2D Protein, cdkn2d.S Protein, CDKN2D Protein, cdkn2d Protein, cdn2d Protein, Cdkn2d Protein

Sujet: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.

Poids moléculaire: 17.5 kDa

NCBI Accession: NP_001791

Pathways: Cycle Cellulaire, Sensory Perception of Sound, Mitotic G1-G1/S Phases, Negative Regulation of intrinsic apoptotic Signaling