ABAT Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714261

Détail du produit

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ABAT protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ABAT (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Autre désignation: Abat (ABAT Produits)

Synonymes: cb880 Protein, fj82a01 Protein, wu:fj82a01 Protein, BA0325 Protein, PSPTO0259 Protein, PSPTO0301 Protein, PSPTO1890 Protein, GABA-AT Protein, GABAT Protein, NPD009 Protein, GABA-T Protein, L-AIBAT Protein, 9630038C02Rik Protein, AI255750 Protein, ENSMUSG00000051226 Protein, Gabaat Protein, Gabat Protein, Gm9851 Protein, I54 Protein, Laibat Protein, X61497 Protein, beta-AlaAT Protein, 4-aminobutyrate aminotransferase Protein, 4-aminobutyrate--2-oxoglutarate transaminase Protein, GABA aminotransferase PLP-dependent PuuE Protein, 4-aminobutyrate aminotransferase, mitochondrial Protein, aspartate aminotransferase family protein Protein, 4-aminobutyrate aminotransferase S homeolog Protein, ABAT Protein, abat Protein, gabT Protein, puuE Protein, gabT-1 Protein, gabT-2 Protein, gabT-3 Protein, CNE01830 Protein, Mmwyl1_0047 Protein, CpipJ_CPIJ008729 Protein, KCR_RS04555 Protein, Bcenmc03_4909 Protein, Hden_0972 Protein, Dbac_2000 Protein, Mesil_2400 Protein, Trad_0121 Protein, abat.S Protein, Abat Protein

Sujet: 4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Poids moléculaire: 53.2 kDa

NCBI Accession: NP_001120920

Pathways: Monocarboxylic Acid Catabolic Process