ABCC8 Protein (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes ABCC8 Protéines
- ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
- Type de proteíne
- Recombinant
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette ABCC8 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human ABCC8 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ABCC8 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- ABCC8 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 8 (ABCC8))
- Autre désignation
- Abcc8 (ABCC8 Produits)
- Synonymes
- ABC36 Protein, HHF1 Protein, HI Protein, HRINS Protein, MRP8 Protein, PHHI Protein, SUR Protein, SUR1 Protein, SUR1delta2 Protein, TNDM2 Protein, D930031B21Rik Protein, Sur Protein, Sur1 Protein, ATP binding cassette subfamily C member 8 Protein, ATP-binding cassette, sub-family C (CFTR/MRP), member 8 Protein, ABCC8 Protein, Abcc8 Protein
- Sujet
- The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternatively spliced transcript variants have been found for this gene.
- Poids moléculaire
- 176.8 kDa
- NCBI Accession
- NP_000343
- Pathways
- Negative Regulation of Hormone Secretion
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