Adenylosuccinate Lyase Protein (ADSL) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714408

Détail du produit

Antigène: Adenylosuccinate Lyase (ADSL)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Adenylosuccinate Lyase protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Adenylosuccinate lyase / ASL (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Adenylosuccinate Lyase (ADSL)

Autre désignation: Adenylosuccinate Lyase (Asl) (ADSL Produits)

Synonymes: fi60b04 Protein, zgc:56061 Protein, wu:fi60b04 Protein, MGC53383 Protein, MGC69239 Protein, adsL Protein, F15C21.8 Protein, F15C21_8 Protein, AMPS Protein, ASASE Protein, ASL Protein, Adl Protein, Asl Protein, purB Protein, adenylosuccinate lyase Protein, adenylosuccinate lyase L homeolog Protein, adenylosuccinase; ASL Protein, Adenylosuccinate lyase Protein, L-Aspartase-like family protein Protein, ADSL Protein, adsl Protein, adsl.L Protein, ASL Protein, purB Protein, purB,adsL Protein, Mrub_2293 Protein, MMAH_RS02975 Protein, Arnit_0089 Protein, Mesil_1058 Protein, Slip_0597 Protein, Trad_2452 Protein, Deba_0652 Protein, Toce_1174 Protein, Acear_2324 Protein, Igag_0272 Protein, Saut_2156 Protein, Fbal_1996 Protein, Ndas_2434 Protein, Ilyop_0196 Protein, Lbys_2961 Protein, MFER_RS02920 Protein, Palpr_2192 Protein, Calni_0061 Protein, Ftrac_3746 Protein, AT1G36280 Protein, Olsu_1764 Protein, Adsl Protein

Sujet: The protein encoded by this gene belongs to the lyase 1 family. It is an essential enzyme involved in purine metabolism, and catalyzes two non-sequential reactions in the de novo purine biosynthetic pathway: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and the conversion of adenylosuccinate (S-AMP) to adenosine monophosphate (AMP). Mutations in this gene are associated with adenylosuccinase deficiency (ADSLD), a disorder marked with psychomotor retardation, epilepsy or autistic features. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 54.7 kDa

NCBI Accession: NP_000017

Pathways: Ribonucleoside Biosynthetic Process