P5CS Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714537

Détail du produit

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette P5CS protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ALDH18A1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: P5CS (ALDH18A1) (Aldehyde Dehydrogenase 18 Family, Member A1 (ALDH18A1))

Autre désignation: Aldh18a1 (ALDH18A1 Produits)

Synonymes: ALDH18A1 Protein, ARCL3A Protein, GSAS Protein, P5CS Protein, PYCS Protein, 2810433K04Rik Protein, AI429789 Protein, Pycs Protein, cb842 Protein, cb899 Protein, pycs Protein, sb:cb881 Protein, wu:fa91f10 Protein, wu:fi05f11 Protein, wu:fi17d12 Protein, aldehyde dehydrogenase 18 family member A1 Protein, aldehyde dehydrogenase 18 family, member A1 Protein, aldehyde dehydrogenase 18 family member A1 L homeolog Protein, ALDH18A1 Protein, aldh18a1 Protein, Aldh18a1 Protein, aldh18a1.L Protein

Sujet: This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene.

Poids moléculaire: 87.1 kDa

NCBI Accession: NP_002851