ALDH2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714541

Détail du produit

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ALDH2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ALDH2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ALDH2 (Aldehyde Dehydrogenase 2 Family (Mitochondrial) (ALDH2))

Autre désignation: Aldh2 (ALDH2 Produits)

Synonymes: aldh2 Protein, aldh2a Protein, zgc:63786 Protein, MGC80785 Protein, aldh-e2 Protein, aldhi Protein, aldm Protein, rf2b Protein, ALDH-E2 Protein, ALDHI Protein, ALDM Protein, Ahd-5 Protein, Ahd5 Protein, aldehyde dehydrogenase 2 family (mitochondrial), tandem duplicate 1 Protein, aldehyde dehydrogenase 2 family (mitochondrial) L homeolog Protein, aldehyde dehydrogenase 2 family (mitochondrial) Protein, aldehyde dehydrogenase 2 Protein, aldehyde dehydrogenase Protein, aldehyde dehydrogenase (NAD(+)) Protein, hypothetical protein Protein, aldehyde dehydrogenase 2, mitochondrial Protein, aldh2.1 Protein, aldh2.L Protein, aldh2 Protein, ALDH2 Protein, RHA1_RS43090 Protein, aldH2 Protein, OE_RS03015 Protein, Aldh2 Protein

Sujet: This protein belongs to the aldehyde dehydrogenase family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of aldehyde dehydrogenase, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of East Asians have the cytosolic isozyme but not the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among East Asians than among Caucasians could be related to the absence of a catalytically active form of the mitochondrial isozyme. The increased exposure to acetaldehyde in individuals with the catalytically inactive form may also confer greater susceptibility to many types of cancer. This gene encodes a mitochondrial isoform, which has a low Km for acetaldehydes, and is localized in mitochondrial matrix. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Nov 2016]

Poids moléculaire: 54.4 kDa

NCBI Accession: NP_000681