ACTN1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714612

Détail du produit

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ACTN1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Alpha-actinin-1 / ACTN1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ACTN1 (Actinin, alpha 1 (ACTN1))

Autre désignation: alpha-Actinin-1,actn1 (ACTN1 Produits)

Synonymes: ACTN1 Protein, actinin Protein, BDPLT15 Protein, 3110023F10Rik Protein, Actn1a Protein, actinin alpha 1 Protein, actinin, alpha 1 Protein, actinin alpha 1 L homeolog Protein, ACTN1 Protein, actn1 Protein, Actn1 Protein, actn1.L Protein

Sujet: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 102.9 kDa

NCBI Accession: NP_001093

Pathways: Cell-Cell Junction Organization