Apoptosis Inhibitor 5 Protein (API5) (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714802

Détail du produit

Antigène: Apoptosis Inhibitor 5 (API5)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Apoptosis Inhibitor 5 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human API5 / MIG8 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Apoptosis Inhibitor 5 (API5)

Autre désignation: Api5,mig8 (API5 Produits)

Synonymes: AAC-11 Protein, AAC11 Protein, AI196452 Protein, api5l1 Protein, sr:nyz021 Protein, zgc:66211 Protein, wu:fb26c03 Protein, API-5B Protein, aac-11 Protein, aac11 Protein, api5 Protein, API-5A Protein, api5-A Protein, MGC83290 Protein, API5 Protein, apoptosis inhibitor 5 Protein, apoptosis inhibitor 5 S homeolog Protein, apoptosis inhibitor 5 L homeolog Protein, API5 Protein, Api5 Protein, api5 Protein, api5.S Protein, api5.L Protein

Sujet: This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 50.6 kDa

NCBI Accession: NP_001136403

Pathways: Growth Factor Binding