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APOBEC3A Protein (Myc-DYKDDDDK Tag)

APOBEC3A Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2714811
  • Antigène Tous les produits APOBEC3A
    APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
    Type de proteíne
    Recombinant
    Origine
    Humain
    Source
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette APOBEC3A protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human APOBEC3A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    APOBEC3A (Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptide-Like 3A (APOBEC3A))
    Autre désignation
    Apobec3a (APOBEC3A Produits)
    Synonymes
    A3A Protein, ARP3 Protein, PHRBN Protein, bK150C2.1 Protein, APOBEC3A Protein, APOBEC3Z1 Protein, apolipoprotein B mRNA editing enzyme catalytic subunit 3A Protein, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A Protein, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z1 Protein, similar to ARP10 protein Protein, APOBEC3A Protein, APOBEC3Z1 Protein
    Sujet
    This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    22.8 kDa
    NCBI Accession
    NP_663745
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