APLP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes APLP2 Protéines
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 3
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette APLP2 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human APPL2 / APLP2 (transcript variant 3) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product APLP2 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
- Autre désignation
- Appl2,aplp2 (APLP2 Produits)
- Synonymes
- HAI Protein, MT-SP1 Protein, MTSP1 Protein, PRSS14 Protein, SNC19 Protein, TADG15 Protein, TMPRSS14 Protein, APLP-2 Protein, APPH Protein, APPL2 Protein, CDEBP Protein, AI790698 Protein, Apph Protein, WALPLP2 Protein, aplp2 B Protein, APLP2 Protein, si:dkey-11k4.3 Protein, aplp2 A Protein, MGC86389 Protein, suppression of tumorigenicity 14 Protein, amyloid beta precursor like protein 2 Protein, amyloid beta (A4) precursor-like protein 2 Protein, amyloid beta (A4) precursor-like protein 2 S homeolog Protein, amyloid beta (A4) precursor-like protein 2 L homeolog Protein, ST14 Protein, APLP2 Protein, Aplp2 Protein, aplp2.S Protein, aplp2 Protein, aplp2.L Protein
- Sujet
- This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer&aposs disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
- Poids moléculaire
- 79.1 kDa
- NCBI Accession
- NP_001135749
- Pathways
- EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour
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