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APLP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

APLP2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2714847
  • Antigène Voir toutes APLP2 Protéines
    APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 3
    Origine
    • 7
    • 3
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette APLP2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human APPL2 / APLP2 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product APLP2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
    Autre désignation
    Appl2,aplp2 (APLP2 Produits)
    Synonymes
    HAI Protein, MT-SP1 Protein, MTSP1 Protein, PRSS14 Protein, SNC19 Protein, TADG15 Protein, TMPRSS14 Protein, APLP-2 Protein, APPH Protein, APPL2 Protein, CDEBP Protein, AI790698 Protein, Apph Protein, WALPLP2 Protein, aplp2 B Protein, APLP2 Protein, si:dkey-11k4.3 Protein, aplp2 A Protein, MGC86389 Protein, suppression of tumorigenicity 14 Protein, amyloid beta precursor like protein 2 Protein, amyloid beta (A4) precursor-like protein 2 Protein, amyloid beta (A4) precursor-like protein 2 S homeolog Protein, amyloid beta (A4) precursor-like protein 2 L homeolog Protein, ST14 Protein, APLP2 Protein, Aplp2 Protein, aplp2.S Protein, aplp2 Protein, aplp2.L Protein
    Sujet
    This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer&aposs disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
    Poids moléculaire
    79.1 kDa
    NCBI Accession
    NP_001135749
    Pathways
    EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour
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