ARHGAP24 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2714878

Détail du produit

Antigène: ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ARHGAP24 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ARHGAP24 / FILGAP (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ARHGAP24 (rho GTPase Activating Protein 24 (ARHGAP24))

Autre désignation: Arhgap24,filgap (ARHGAP24 Produits)

Synonymes: FILGAP Protein, RC-GAP72 Protein, RCGAP72 Protein, p73 Protein, p73RhoGAP Protein, 0610025G21Rik Protein, si:ch211-65i12.2 Protein, Rho GTPase activating protein 24 Protein, ARHGAP24 Protein, Arhgap24 Protein, arhgap24 Protein

Sujet: This gene encodes a Rho-GTPase activating protein, which is specific for the small GTPase family member Rac. Binding of the encoded protein by filamin A targets it to sites of membrane protrusion, where it antognizes Rac. This results in suppression of lamellae formation and promotion of retraction to regulate cell polarity. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 84.1 kDa

NCBI Accession: NP_001020787

Pathways: Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus