ARNT2 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2714934

Détail du produit

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ARNT2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ARNT2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Autre désignation: Arnt2 (ARNT2 Produits)

Synonymes: bHLHe1 Protein, Hif-2b Protein, mKIAA0307 Protein, Arnt Protein, arnt2X Protein, arnt2a Protein, chunp6921 Protein, zfARNT2 Protein, zfARNT2a Protein, zfARNT2b Protein, zfARNT2c Protein, arnt2 Protein, MGC53123 Protein, arnt.2 Protein, MGC68805 Protein, ARNT2 Protein, aryl hydrocarbon receptor nuclear translocator 2 Protein, aryl-hydrocarbon receptor nuclear translocator 2 Protein, aryl hydrocarbon receptor nuclear translocator 2 S homeolog Protein, aryl hydrocarbon receptor nuclear translocator S homeolog Protein, ARNT2 Protein, Arnt2 Protein, arnt2 Protein, arnt2.S Protein, arnt.S Protein, LOC100067423 Protein

Sujet: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Poids moléculaire: 78.5 kDa

NCBI Accession: NP_055677

Pathways: L'effet Warburg