ATP6V1C1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2715057

Détail du produit

Antigène: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ATP6V1C1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ATP6V1C1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ATP6V1C1 (ATPase, H+ Transporting, Lysosomal 42kDa, V1 Subunit C1 (ATP6V1C1))

Autre désignation: Atp6v1c1 (ATP6V1C1 Produits)

Synonymes: ATP6C Protein, ATP6D Protein, VATC Protein, Vma5 Protein, 1700025B18Rik Protein, U13839 Protein, vatC Protein, ATPase Protein, atp6v1c1 Protein, si:zc215i13.2 Protein, wu:fd12h05 Protein, atp6v1c1l Protein, zgc:92684 Protein, ATPase H+ transporting V1 subunit C1 Protein, ATPase, H+ transporting, lysosomal V1 subunit C1 Protein, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 Protein, ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 L homeolog Protein, ATPase, H+ transporting, lysosomal, V1 subunit C1a Protein, ATPase, H+ transporting, lysosomal, V1 subunit C1b Protein, ATP6V1C1 Protein, Atp6v1c1 Protein, atp6v1c1 Protein, atp6v1c1.L Protein, atp6v1c1a Protein, atp6v1c1b Protein

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene is one of two genes that encode the V1 domain C subunit proteins and is found ubiquitously. This C subunit is analogous but not homologous to gamma subunit of F-ATPases. Previously, this gene was designated ATP6D.

Poids moléculaire: 43.8 kDa

NCBI Accession: NP_001686

Pathways: Transition Metal Ion Homeostasis, Proton Transport