DDX39B Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715155

Détail du produit

Antigène: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DDX39B protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human BAT1 / UAP56 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))

Autre désignation: Bat1,uap56 (DDX39B Produits)

Synonymes: BAT1 Protein, D6S81E Protein, UAP56 Protein, Bat1 Protein, Bat1a Protein, p47 Protein, 0610030D10Rik Protein, AI428441 Protein, Bat-1 Protein, D17H6S81E Protein, D17H6S81E-1 Protein, D6S81Eh Protein, bat1 Protein, zgc:63773 Protein, DExD-box helicase 39B Protein, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B Protein, DDX39B Protein, Ddx39b Protein, ddx39b Protein

Sujet: Splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint. Has both RNA-stimulated ATP binding/hydrolysis activity and ATP-dependent RNA unwinding activity. Even with the stimulation of RNA, the ATPase activity is weak. Can only hydrolyze ATP but not other NTPs. The RNA stimulation of ATPase activity does not have a strong preference for the sequence and length of the RNA. However, ssRNA stimulates the ATPase activity much more strongly than dsRNA. Can unwind 5' or 3' overhangs or blunt end RNA duplexes in vitro. The ATPase and helicase activities are not influenced by U2AF2 the effect of ALYREF/THOC4 is reported conflictingly with [PubMed:23299939] reporting a stimulatory effect. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 48.8 kDa

NCBI Accession: NP_004631

Pathways: Ribonucleoprotein Complex Subunit Organization