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BBS4 Protein (Myc-DYKDDDDK Tag)

BBS4 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2715167
  • Antigène Voir toutes BBS4 Protéines
    BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
    Type de proteíne
    Recombinant
    Origine
    • 2
    • 1
    Humain
    Source
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette BBS4 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human BBS4 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product BBS4 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    BBS4 (Bardet-Biedl Syndrome 4 (BBS4))
    Autre désignation
    Bbs4 (BBS4 Produits)
    Synonymes
    CG13232 Protein, Dmel\\CG13232 Protein, zgc:152964 Protein, AW537059 Protein, AW742241 Protein, D9Ertd464e Protein, Bardet-Biedl syndrome 4 Protein, bardet-biedl syndrome 4 Protein, Bardet-Biedl syndrome 4 (human) Protein, BBS4 Protein, bbs4 Protein, Bbs4 Protein
    Sujet
    This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by severe pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse. The similar phenotypes exhibited by mutations in BBS gene family members are likely due to the protein&aposs shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene has sequence similarity to O-linked N-acetylglucosamine (O-GlcNAc) transferases in plants and archaebacteria and in human forms a multi-protein "BBSome" complex with seven other BBS proteins. Alternate splicing results in multiple transcript variants.
    Poids moléculaire
    58.1 kDa
    NCBI Accession
    NP_149017
    Pathways
    Signalisation Hedgehog, Tube Formation, Maintenance of Protein Location
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