BBS7 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2715168

Détail du produit

Antigène: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette BBS7 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human BBS7 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: BBS7 (Bardet-Biedl Syndrome 7 (BBS7))

Autre désignation: Bbs7 (BBS7 Produits)

Synonymes: BBS7 Protein, bbs2l1 Protein, BBS2L1 Protein, id:ibd5048 Protein, zgc:153772 Protein, 8430406N16Rik Protein, Bardet-Biedl syndrome 7 Protein, bardet-biedl syndrome 7 Protein, Bardet-Biedl syndrome 7 L homeolog Protein, Bardet-Biedl syndrome 7 (human) Protein, BBS7 Protein, bbs7 Protein, MICPUN_100192 Protein, MICPUCDRAFT_16331 Protein, bbs7.L Protein, Bbs7 Protein

Sujet: This gene encodes one of eight proteins that form the BBSome complex containing BBS1, BBS2, BBS4, BBS5, BBS7, BBS8, BBS9 and BBIP10. The BBSome complex is believed to recruit Rab8(GTP) to the primary cilium and promote ciliogenesis. The BBSome complex assembly is mediated by a complex composed of three chaperonin-like BBS proteins (BBS6, BBS10, and BBS12) and CCT/TRiC family chaperonins. Mutations in this gene are implicated in Bardet-Biedl syndrome, a genetic disorder whose symptoms include obesity, retinal degeneration, polydactyly and nephropathy however, mutations in this gene and the BBS8 gene are thought to play a minor role and mutations in chaperonin-like BBS genes are found to be a major contributor to disease development in a multiethnic Bardet-Biedl syndrome patient population. Two transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Oct 2014].

Poids moléculaire: 75.3 kDa

NCBI Accession: NP_060660

Pathways: Signalisation Hedgehog