CRYBA1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2715237

Détail du produit

Antigène: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CRYBA1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Beta-crystallin A3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CRYBA1 (Crystallin, beta A1 (CRYBA1))

Autre désignation: beta-Crystallin a3 (CRYBA1 Produits)

Synonymes: CRYB1 Protein, CTRCT10 Protein, BA3/A1 Protein, Cryb Protein, BA3A1C Protein, beta-A3 Protein, cryba1 Protein, zgc:92688 Protein, CRYBA3 Protein, cryb1 Protein, zgc:92720 Protein, crystallin beta A1 Protein, crystallin, beta A1 Protein, crystallin, beta A1a Protein, crystallin beta A1 L homeolog Protein, crystallin, beta A1b Protein, CRYBA1 Protein, Cryba1 Protein, cryba1a Protein, cryba1.L Protein, cryba1 Protein, cryba1b Protein

Sujet: Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.

Poids moléculaire: 25 kDa

NCBI Accession: NP_005199