CAMK2A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2716968

Détail du produit

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CAMK2A protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CAMK2A (Calcium/calmodulin-Dependent Protein Kinase II alpha (CAMK2A))

Abstract: CAMK2A Produits

Synonymes: camk2 Protein, camk2b Protein, zgc:112538 Protein, zgc:123320 Protein, CAMKA Protein, CaMKII Protein, R74975 Protein, mKIAA0968 Protein, PK2CDD Protein, PKCCD Protein, calcium/calmodulin dependent protein kinase II alpha Protein, calcium/calmodulin dependent protein kinase (CaM kinase) II alpha S homeolog Protein, calcium/calmodulin-dependent protein kinase II alpha Protein, CAMK2A Protein, camk2a.S Protein, camk2a Protein, Camk2a Protein

Sujet: The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Poids moléculaire: 55.1 kDa

NCBI Accession: NP_057065

Pathways: Signalisation WNT, Interferon-gamma Pathway, Myometrial Relaxation and Contraction