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COQ6 Protein (His tag)

COQ6 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2718741
  • Antigène Voir toutes COQ6 Protéines
    COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
    Type de proteíne
    Recombinant
    Origine
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 4
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette COQ6 protéine est marqué à la His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human COQ6 (N-term HIS tag, transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product COQ6 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    COQ6 (Coenzyme Q6, Monooxygenase (COQ6))
    Autre désignation
    Coenzyme q6 Homolog, Monooxygenase (S. Cerevisiae) (Coq6) (COQ6 Produits)
    Synonymes
    CGI10 Protein, COQ10D6 Protein, 5930427M12Rik Protein, AW742344 Protein, zgc:153379 Protein, coq6 Protein, coenzyme Q6, monooxygenase Protein, coenzyme Q6 monooxygenase Protein, Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial Protein, coenzyme Q6 monooxygenase L homeolog Protein, COQ6 Protein, Coq6 Protein, coq-6 Protein, coq6 Protein, coq6.L Protein
    Sujet
    The protein encoded by this gene belongs to the ubiH/COQ6 family. It is an evolutionarily conserved monooxygenase required for the biosynthesis of coenzyme Q10 (or ubiquinone), which is an essential component of the mitochondrial electron transport chain, and one of the most potent lipophilic antioxidants implicated in the protection of cell damage by reactive oxygen species. Knockdown of this gene in mouse and zebrafish results in decreased growth due to increased apoptosis. Mutations in this gene are associated with autosomal recessive coenzyme Q10 deficiency-6 (COQ10D6), which manifests as nephrotic syndrome with sensorineural deafness. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Poids moléculaire
    50.7 kDa
    NCBI Accession
    NP_872282
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