DAZL Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2719233

Détail du produit

Antigène: DAZL (Deleted in Azoospermia-Like (DAZL))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DAZL protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DAZL protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DAZL (Deleted in Azoospermia-Like (DAZL))

Autre désignation: Dazl (DAZL Produits)

Synonymes: DAZH Protein, DAZL1 Protein, DAZLA Protein, SPGYLA Protein, DAZL Protein, Xdazl Protein, dazh Protein, dazl1 Protein, dazla Protein, spgyla Protein, dazl-B Protein, dazl-a Protein, Daz-like Protein, Dazh Protein, Dazl1 Protein, Dazla Protein, Tpx-2 Protein, Tpx2 Protein, deleted in azoospermia like Protein, deleted in azoospermia-like Protein, deleted in azoospermia-like L homeolog Protein, DAZL Protein, dazl Protein, Dazl Protein, dazl.L Protein

Sujet: The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 33 kDa

NCBI Accession: NP_001342