DICER1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719477

Détail du produit

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DICER1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DICER1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Zhang, Li, Deng, Liu, Chen, Tang, Wang, Cao, Fang, Wen, Xu, Chen, Shi, Li, Xie, Tang: "Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents." dans: Nucleic acids research, Vol. 44, Issue 8, pp. 3629-42, (2016) (PubMed).

Détail du antigène

Antigène: DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

Autre désignation: Dicer1 (DICER1 Produits)

Synonymes: dcr1 Protein, dicer Protein, herna Protein, DICER1 Protein, dicer1 Protein, 1110006F08Rik Protein, D12Ertd7e Protein, mKIAA0928 Protein, DCR1 Protein, Dicer Protein, HERNA Protein, MNG1 Protein, DICER Protein, fc39d11 Protein, fc74b05 Protein, wu:fc39d11 Protein, wu:fc74b05 Protein, dicer 1, ribonuclease III Protein, endoribonuclease Dicer Protein, dicer 1, ribonuclease III S homeolog Protein, dicer 1, ribonuclease type III Protein, dicer 1 ribonuclease III Protein, DICER1 Protein, CpipJ_CPIJ010534 Protein, dicer1 Protein, dicer1.S Protein, Dicer1 Protein

Sujet: This gene encodes a protein possessing an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus. The encoded protein functions as a ribonuclease and is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 218.5 kDa

NCBI Accession: NP_803187

Pathways: Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization