DIRAS3 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2719498

Détail du produit

Antigène: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DIRAS3 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human DIRAS3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Zhang, Lu, Mao, Ahmed, Yang, Zhou, Jennings, Rodriguez-Aguayo, Lopez-Berestein, Miranda, Qiao, Baladandayuthapani, Li, Sood, Liu, Le, Bast: "CDK5 Regulates Paclitaxel Sensitivity in Ovarian Cancer Cells by Modulating AKT Activation, p21Cip1- and p27Kip1-Mediated G1 Cell Cycle Arrest and Apoptosis." dans: PLoS ONE, Vol. 10, Issue 7, pp. e0131833, (2015) (PubMed).

Détail du antigène

Antigène: DIRAS3 (DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3))

Autre désignation: Diras3 (DIRAS3 Produits)

Synonymes: DIRAS3 Protein, arhi Protein, noey2 Protein, ARHI Protein, NOEY2 Protein, DIRAS family GTPase 3 Protein, DIRAS family GTP binding RAS like 3 Protein, DIRAS3 Protein, diras3 Protein

Sujet: This gene encodes a member of the ras superfamily. This gene is imprinted gene with monoallelic expression of the paternal allele which is associated with growth suppression. The encoded protein acts as a tumor suppressor whose function is abrogated in many ovarian and breast cancers. This protein may also play a role autophagy in certain cancer cells by regulating the autophagosome initiation complex.

Poids moléculaire: 25.7 kDa

NCBI Accession: NP_004666