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DCLK2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DCLK2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2719686
  • Antigène Voir toutes DCLK2 Protéines
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 4
    • 2
    • 1
    Humain
    Source
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette DCLK2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Doublecortin-like kinase 2 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DCLK2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
    Autre désignation
    Doublecortin-Like Kinase 2 (DCLK2 Produits)
    Synonymes
    CL2 Protein, CLICK-II Protein, CLICK2 Protein, CLIK2 Protein, DCAMKL2 Protein, DCDC3 Protein, DCDC3B Protein, DCK2 Protein, 6330415M09Rik Protein, AU044875 Protein, Click-II Protein, Dcamkl2 Protein, DCLK2 Protein, cb572 Protein, dclk Protein, sb:cb572 Protein, si:dkey-180n16.1 Protein, Dck2 Protein, RGD1308384 Protein, doublecortin like kinase 2 Protein, doublecortin-like kinase 2 Protein, doublecortin-like kinase 2a Protein, DCLK2 Protein, Dclk2 Protein, dclk2a Protein
    Sujet
    This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
    Poids moléculaire
    83.4 kDa
    NCBI Accession
    NP_001035350
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