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DTX2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DTX2 Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2719805
  • Antigène Voir toutes DTX2 Protéines
    DTX2 (Deltex Homolog 2 (DTX2))
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 3
    • 1
    Humain
    Source
    • 2
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette DTX2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human DTX2 / RNF58 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DTX2 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    DTX2 (Deltex Homolog 2 (DTX2))
    Autre désignation
    Dtx2,rnf58 (DTX2 Produits)
    Synonymes
    RNF58 Protein, 2610524D08Rik Protein, AA408415 Protein, AU022494 Protein, Deltex2 Protein, dtx2 Protein, deltex E3 ubiquitin ligase 2 Protein, probable E3 ubiquitin-protein ligase DTX2 Protein, deltex 2, E3 ubiquitin ligase Protein, deltex 2, E3 ubiquitin ligase S homeolog Protein, DTX2 Protein, Dtx2 Protein, LOC735784 Protein, LOC747633 Protein, dtx2 Protein, dtx2.S Protein
    Sujet
    Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProtKB/Swiss-Prot Function]
    Poids moléculaire
    67.1 kDa
    NCBI Accession
    NP_065943
    Pathways
    Signalisation Notch
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