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Dynamin 1-Like Protein (DNM1L) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

DNM1L Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2719860
  • Antigène Voir toutes Dynamin 1-Like (DNM1L) Protéines
    Dynamin 1-Like (DNM1L)
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 5
    • 2
    • 2
    • 1
    Humain
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Dynamin 1-Like protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human Dynamin-1-like protein (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product DNM1L Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Guo, Lu, Huang, Wu, Zhang, Yu, Zhang, Bao, He, Chen, Jia: "Protective role of PGC-1α in diabetic nephropathy is associated with the inhibition of ROS through mitochondrial dynamic remodeling." dans: PLoS ONE, Vol. 10, Issue 4, pp. e0125176, (2015) (PubMed).

  • Antigène
    Dynamin 1-Like (DNM1L)
    Autre désignation
    Dynamin-1-Like Protein (DNM1L Produits)
    Synonymes
    DLP1 Protein, DRP1 Protein, DVLP Protein, DYMPLE Protein, EMPF Protein, HDYNIV Protein, 6330417M19Rik Protein, AI450666 Protein, Dlp1 Protein, Dnmlp1 Protein, Drp1 Protein, python Protein, Dnml1 Protein, dnm1l Protein, MGC53850 Protein, zgc:66163 Protein, DNM1L Protein, 18.m06247 Protein, CG3210 Protein, DRP Protein, Dmel\CG3210 Protein, Dnm1/Drp1 Protein, Drp Protein, Drp-1 Protein, drp-1 Protein, drp1 Protein, frat Protein, l(2)22Fc Protein, l(2)22Fd Protein, l(2)ND2 Protein, l(2)ND3 Protein, dynamin 1 like Protein, dynamin 1-like Protein, dynamin 1-like L homeolog Protein, dynamin-1-like Protein, dynamin-1-like protein Protein, dynamin-like protein Protein, Dynamin related protein 1 Protein, DNM1L Protein, Dnm1l Protein, dnm1l.L Protein, dnm1l Protein, LOC100369408 Protein, LOC411472 Protein, dyn1 Protein, cgd1_580 Protein, EHI_052740 Protein, PVX_092875 Protein, BBOV_II002980 Protein, Drp1 Protein
    Sujet
    This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
    Poids moléculaire
    81.7 kDa
    NCBI Accession
    NP_036192
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