EDARADD Protein (Transcript Variant B) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719929

Détail du produit

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant B

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette EDARADD protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human EDARADD (transcript variant B) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: EDARADD (EDAR-Associated Death Domain (EDARADD))

Autre désignation: Edaradd (EDARADD Produits)

Synonymes: 1810032E07Rik Protein, 5830469M23Rik Protein, A630043P06 Protein, cr Protein, ECTD11A Protein, ECTD11B Protein, ED3 Protein, EDA3 Protein, EDAR (ectodysplasin-A receptor)-associated death domain Protein, EDAR associated death domain Protein, Edaradd Protein, EDARADD Protein

Sujet: This gene was identified by its association with ectodermal dysplasia, a genetic disorder characterized by defective development of hair, teeth, and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein, and is found to interact with EDAR, a death domain receptor known to be required for the development of hair, teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR, this protein acts as an adaptor, and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Poids moléculaire: 23.5 kDa

NCBI Accession: NP_542776

Pathways: Ubiquitin Proteasome Pathway