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p300 Protein (DYKDDDDK Tag)

EP300 Origine: Humain Hôte: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2720219
  • Antigène Voir toutes p300 (EP300) Protéines
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    Type de proteíne
    Recombinant
    Origine
    • 4
    • 1
    • 1
    Humain
    Source
    • 4
    • 1
    • 1
    • 1
    Insect cells (Sf9)
    Purification/Conjugué
    Cette p300 protéine est marqué à la DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human EP300 / P300 (C-term DDK tag) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product EP300 Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl pH 8.0, 150 mM NaCl, 20 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Martinez, Abe, Hong, Molyneux, Yarnell, Löhr, Driever, Acosta, Arcos-Burgos, Muenke: "An Ultraconserved Brain-Specific Enhancer Within ADGRL3 (LPHN3) Underpins Attention-Deficit/Hyperactivity Disorder Susceptibility." dans: Biological psychiatry, Vol. 80, Issue 12, pp. 943-954, (2016) (PubMed).

  • Antigène
    p300 (EP300) (E1A Binding Protein P300 (EP300))
    Autre désignation
    Ep300,p300 (EP300 Produits)
    Synonymes
    KAT3B Protein, RSTS2 Protein, p300 Protein, A430090G16 Protein, A730011L11 Protein, p300 HAT Protein, E1A binding protein p300 Protein, histone acetyltransferase p300 Protein, EP300 Protein, LOC446056 Protein, ep300 Protein, Ep300 Protein
    Sujet
    This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer.
    Poids moléculaire
    75 kDa
    NCBI Accession
    NP_001420
    Pathways
    Signalisation p53, Signalisation Notch, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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