ERCC6 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2720440

Détail du produit

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ERCC6 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human ERCC6 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Autre désignation: Ercc6 (ERCC6 Produits)

Synonymes: ARMD5 Protein, CKN2 Protein, COFS Protein, COFS1 Protein, CSB Protein, RAD26 Protein, UVSS1 Protein, 4732403I04 Protein, C130058G22Rik Protein, ercc6 Protein, Ercc6 Protein, ERCC excision repair 6, chromatin remodeling factor Protein, excision repair cross-complementing rodent repair deficiency, complementation group 6 Protein, excision repair cross-complementation group 6 Protein, DNA excision repair protein ERCC-6 Protein, ERCC6 Protein, Ercc6 Protein, ercc6 Protein, LOC100719487 Protein

Sujet: This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3&apos splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3 (GeneID:267004), which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

Poids moléculaire: 168.2 kDa

NCBI Accession: NP_000115

Pathways: Réparation de l'ADN, Chromatin Binding