POLR2M Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722004

Détail du produit

Antigène: POLR2M (GRINL1A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A (GRINL1A))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette POLR2M protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A), transcript variant 1 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Montesinos-Rongen, Purschke, Brunn, May, Nordhoff, Marcus, Deckert: "Primary Central Nervous System (CNS) Lymphoma B Cell Receptors Recognize CNS Proteins." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1312-9, (2015) (PubMed).

Détail du antigène

Antigène: POLR2M (GRINL1A) (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate-Like 1A (GRINL1A))

Abstract: GRINL1A Produits

Synonymes: GCOM1 Protein, GRINL1A Protein, Gdown Protein, Gdown1 Protein, AA407243 Protein, AA408799 Protein, AI303746 Protein, AW553238 Protein, D9Wsu138e Protein, Grinl1a Protein, mKIAA4185 Protein, Glurr Protein, RNA polymerase II subunit M Protein, polymerase (RNA) II (DNA directed) polypeptide M Protein, POLR2M Protein, Polr2m Protein

Sujet: This gene encodes a subunit of a specific form of RNA polymerase II termed Pol II(G). The encoded protein may act as a negative regulator of transcriptional activation by the Mediator complex. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 4. Readthrough transcription between this gene and the neighboring upstream gene MYZAP (myocardial zonula adherens protein) is represented with GeneID 145781.

Poids moléculaire: 41.6 kDa

NCBI Accession: NP_056347