Glutaredoxin 2 Protein (GRX2) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722017

Détail du produit

Antigène: Glutaredoxin 2 (GRX2)

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Glutaredoxin 2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Glutaredoxin-2 / GLRX2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: Glutaredoxin 2 (GRX2)

Autre désignation: Glutaredoxin-2,glrx2 (GRX2 Produits)

Synonymes: ECK1049 Protein, JW1051 Protein, CGI-133 Protein, GRX2 Protein, 1700010P22Rik Protein, AI645710 Protein, Grx2 Protein, glutaredoxin 2 (Grx2) Protein, glutaredoxin Grx2 Protein, thioredoxin Protein, glutaredoxin 2 Protein, glutaredoxin 2 (thioltransferase) Protein, grxB Protein, grx2 Protein, AF_RS10790 Protein, GLRX2 Protein, Glrx2 Protein

Sujet: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression.

Poids moléculaire: 18.5 kDa

NCBI Accession: NP_057150

Pathways: Cell RedoxHomeostasis