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Osteoactivin Protein (GPNMB) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

GPNMB Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2722179
  • Antigène Voir toutes Osteoactivin (GPNMB) Protéines
    Osteoactivin (GPNMB)
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 1
    Origine
    • 14
    • 3
    Humain
    Source
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Osteoactivin protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human GPNMB / HGFIN (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GPNMB Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Lin, Li, Xing, Hu, Liang, Han, Wang, Hawke, Wang, Zhang, Wei, Ma, Park, Zhou, Zhou, Hu, Zhou, Marks, Liang, Hung, Lin, Yang: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).

  • Antigène
    Osteoactivin (GPNMB)
    Autre désignation
    Gpnmb,hgfin (GPNMB Produits)
    Synonymes
    HGFIN Protein, NMB Protein, DC-HIL Protein, Dchil Protein, ipd Protein, glycoprotein nmb Protein, glycoprotein (transmembrane) nmb Protein, glycoprotein nmb L homeolog Protein, Gpnmb Protein, GPNMB Protein, gpnmb.L Protein
    Sujet
    The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.
    Poids moléculaire
    61.5 kDa
    NCBI Accession
    NP_001005340
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