Osteoactivin Protein (GPNMB) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2722179

Cette protéine Recombinant Osteoactivin est produite dans HEK-293 Cells. Il y a 1 publication disponible.

Aperçu rapide pour Osteoactivin Protein (GPNMB) (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2722179)

Antigène: Osteoactivin (GPNMB)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Attributs du protein: Transcript Variant 1

Purification/Conjugué: Cette Osteoactivin protéine est marqué à la Myc-DYKDDDDK Tag.

Attributs du produit:

• Recombinant human GPNMB / HGFIN (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Référence

Lin, Li, Xing, Hu, Liang, Han, Wang, Hawke, Wang, Zhang, Wei, Ma, Park, Zhou, Zhou, Hu, Zhou, Marks, Liang, Hung, Lin, Yang: "The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer." dans: Nature cell biology, Vol. 18, Issue 2, pp. 213-24, (2016) (PubMed).

Détail du antigène

Antigène: Osteoactivin (GPNMB)

Autre désignation: Gpnmb,hgfin

Sujet: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 61.5 kDa

NCBI Accession: NP_001005340