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GRAP Protein (Myc-DYKDDDDK Tag)

GRAP Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2722222
  • Antigène Voir toutes GRAP Protéines
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Type de proteíne
    Recombinant
    Origine
    • 2
    • 1
    • 1
    Humain
    Source
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette GRAP protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human GRAP protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product GRAP Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    GRAP (GRB2-Related Adaptor Protein (GRAP))
    Autre désignation
    Grap (GRAP Produits)
    Synonymes
    8430435N19Rik Protein, BB233594 Protein, GRAP Protein, grap Protein, zgc:110202 Protein, MGC109892 Protein, si:dkeyp-9d4.1 Protein, Grap Protein, GRB2-related adaptor protein Protein, GRB2-related adapter protein Protein, GRB2-related adaptor protein a Protein, GRB2-related adaptor protein b Protein, GRAP Protein, Grap Protein, LOC489534 Protein, grapa Protein, grapb Protein, LOC100727005 Protein
    Sujet
    This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
    Poids moléculaire
    25.2 kDa
    NCBI Accession
    NP_006604
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