IRF4 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723795

Détail du produit

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IRF4 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human IRF4 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IRF4 (Interferon Regulatory Factor 4 (IRF4))

Autre désignation: Irf4 (IRF4 Produits)

Synonymes: LSIRF Protein, MUM1 Protein, NF-EM5 Protein, AI385587 Protein, IRF-4 Protein, Spip Protein, IRF4 Protein, si:ch73-170d1.2 Protein, irf4 Protein, interferon regulatory factor 4 Protein, interferon regulatory factor 4a Protein, Interferon regulatory factor 4 Protein, PWWP domain-containing protein MUM1 Protein, IRF4 Protein, Irf4 Protein, irf4a Protein, irf4 Protein, LOC612320 Protein, LOC100068881 Protein

Sujet: The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(614)(p25q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene.

Poids moléculaire: 51.6 kDa

NCBI Accession: NP_002451

Pathways: Chromatin Binding