IRF9 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2723813

Détail du produit

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette IRF9 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human IRF9 / ISGF3G protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: IRF9 (Interferon Regulatory Factor 9 (IRF9))

Autre désignation: Irf9,isgf3g (IRF9 Produits)

Synonymes: IRF-9 Protein, ISGF3 Protein, ISGF3G Protein, p48 Protein, zgc:92097 Protein, Irf-9 Protein, Isgf3g Protein, interferon regulatory factor 9 Protein, IRF9 Protein, irf9 Protein, Irf9 Protein

Sujet: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 43.5 kDa

NCBI Accession: NP_006075

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C