KCNQ4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Antigène Voir toutes KCNQ4 Protéines
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
- Type de proteíne
- Recombinant
- Attributs du protein
- Transcript Variant 2
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette KCNQ4 protéine est marqué à la Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Attributs du produit
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- Recombinant human KCNQ4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Pureté
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KCNQ4 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Commentaires
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
- Autre désignation
- Kcnq4 (KCNQ4 Produits)
- Synonymes
- KCNQ4 Protein, k(v)7.4 Protein, kv7.4 Protein, DFNA2 Protein, DFNA2A Protein, KV7.4 Protein, potassium voltage-gated channel subfamily Q member 4 Protein, potassium channel, voltage gated KQT-like subfamily Q, member 4 Protein, potassium voltage-gated channel, subfamily Q, member 4 Protein, KCNQ4 Protein, kcnq4 Protein, Kcnq4 Protein
- Sujet
- Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors. [UniProtKB/Swiss-Prot Function]
- Poids moléculaire
- 71 kDa
- NCBI Accession
- NP_751895
- Pathways
- Sensory Perception of Sound
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