KIRREL2 Protein (His tag)

N° du produit ABIN2724260

Détail du produit

Antigène: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette KIRREL2 protéine est marqué à la His tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human KIRREL2 (full length, N-term HIS tag, transcript variant 1) protein expressed in E.coli.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: KIRREL2 (Kin of IRRE Like 2 (Drosophila) (KIRREL2))

Autre désignation: Kirrel2 (KIRREL2 Produits)

Synonymes: nlg1 Protein, neph3 Protein, filtrin Protein, FILTRIN Protein, NEPH3 Protein, NLG1 Protein, C330019F22Rik Protein, cb33 Protein, kirrel3 Protein, sb:cb33 Protein, si:dkey-29g23.1 Protein, wu:fb74e02 Protein, kirre like nephrin family adhesion molecule 2 Protein, kin of IRRE like 2 (Drosophila) Protein, kirre like nephrin family adhesion molecule 3, like Protein, kirrel2 Protein, KIRREL2 Protein, Kirrel2 Protein, kirrel3l Protein

Sujet: This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.

Poids moléculaire: 66.9 kDa

NCBI Accession: NP_115499