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Kringle Containing Transmembrane Protein 2 (KREMEN2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) Protein

KREMEN2 Origine: Humain Source: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD
N° du produit ABIN2724424
$888.80
Plus frais de port $45.00 et $24.00 pour carboglace
20 μg
local_shipping Destination: Etats-Unis
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  • Nom de la protéine
    Type de proteíne
    Recombinant
    Attributs du protein
    Transcript Variant 2
    Origine
    Humain
    Source
    HEK-293 Cells
    Purification/Conjugué
    Cette KREMEN2 protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Specificité
    Optimal preservation of protein structure, post-translational modifications and functions.
    Attributs du produit
    • Recombinant human Kremen protein 2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    > 50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Nom de la protéine
    Synonymes
    krm2, KREMEN2, MGC147633, KRM2, 2900054E04Rik, Krm2, kringle containing transmembrane protein 2 S homeolog, kringle containing transmembrane protein 2, kremen2.S, KREMEN2, kremen2, Kremen2
    Sujet
    This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene.
    Poids moléculaire
    42.3 kDa
    NCBI Accession
    NP_078783
    Pathways
    Signalisation WNT
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