LRRFIP2 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2724952

Détail du produit

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LRRFIP2 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human LRRFIP2 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: LRRFIP2 (Leucine Rich Repeat (In FLII) Interacting Protein 2 (LRRFIP2))

Autre désignation: Lrrfip2 (LRRFIP2 Produits)

Synonymes: HUFI-2 Protein, 5133400F20Rik Protein, AI850587 Protein, wu:fj34c02 Protein, zgc:113956 Protein, zgc:63771 Protein, LRR binding FLII interacting protein 2 Protein, leucine rich repeat (in FLII) interacting protein 2 Protein, leucine rich repeat (in FLII) interacting protein 2 L homeolog Protein, LRRFIP2 Protein, Lrrfip2 Protein, lrrfip2 Protein, lrrfip2.L Protein

Sujet: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex.

Poids moléculaire: 48.1 kDa

NCBI Accession: NP_001127841