MAPK10 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725409

Détail du produit

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 1

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MAPK10 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MAPK10 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Autre désignation: Mapk10 (MAPK10 Produits)

Synonymes: MAPK10 Protein, zgc:123234 Protein, DKFZp459H0638 Protein, Jnk3 Protein, SAPKC Protein, SAPb Protein, Serk2 Protein, JNK3 Protein, JNK3A Protein, PRKM10 Protein, SAPK1b Protein, p493F12 Protein, p54bSAPK Protein, C230008H04Rik Protein, JNK3B1 Protein, JNK3B2 Protein, SAPK(beta) Protein, ATMPK10 Protein, MAP kinase 10 Protein, mitogen-activated protein kinase 8 S homeolog Protein, mitogen-activated protein kinase 10 Protein, mitogen activated protein kinase 10 Protein, MAP kinase 10 Protein, mapk8.S Protein, MAPK10 Protein, mapk10 Protein, Mapk10 Protein, MPK10 Protein

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Poids moléculaire: 48.4 kDa

NCBI Accession: NP_002744

Pathways: Signalisation MAPK, Signalisation WNT, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades