MAPK7 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

N° du produit ABIN2725433

Détail du produit

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 3

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MAPK7 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human MAPK7 / ERK5 (transcript variant 3) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: Mapk7,erk5 (MAPK7 Produits)

Synonymes: BMK1 Protein, ERK4 Protein, ERK5 Protein, PRKM7 Protein, Erk5-T Protein, ATMPK7 Protein, F8D23.5 Protein, F8D23_5 Protein, MAP kinase 7 Protein, Bmk1 Protein, Erk5 Protein, Prkm7 Protein, ERK-5 Protein, bmk1 Protein, erk4 Protein, mapk7 Protein, prkm7 Protein, mitogen-activated protein kinase 7 Protein, MAP kinase 7 Protein, mitogen-activated protein kinase 7 L homeolog Protein, MAPK7 Protein, Mapk7 Protein, MPK7 Protein, mapk7.L Protein

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Poids moléculaire: 88.2 kDa

NCBI Accession: NP_002740

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling